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含硼替佐米的联合化疗方案治疗初诊多发性骨髓瘤患者的疗效比较 被引量:16

Analysis of Bortezomib-containing combinations in newly-diagnosed multiple myeloma patients: a comparative study
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摘要 多发性骨髓瘤(multiple myeloma,MM)是一种以浆细胞异常克隆和增殖为特征的血液系统恶性疾病,常规化疗方案如MP(马法兰+泼尼松)、VAD(长春新碱+阿霉素+地塞米松)、M2(卡氮芥+马法兰+泼尼松+长春新碱+环磷酰胺)方案治疗后患者完全缓解(CR)率为3%~10%,中位生存期约为3年。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2014年第5期448-450,共3页 Chinese Journal of Hematology
基金 国家自然科学基金(81172249)
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参考文献12

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同被引文献140

  • 1杨永健,钱震.硼替佐米为主化疗方案治疗多发性骨髓瘤12例疗效分析[J].兵团医学,2013(4):27-29. 被引量:1
  • 2邱录贵.多发性骨髓瘤的发病与国人特点[J].中国实用内科杂志:临床前沿版,2006,26(6):886-888. 被引量:52
  • 3董作仁,姚丽.多发性骨髓瘤的临床表现与诊断思维提示[J].中国全科医学,2007,10(18):1497-1498. 被引量:15
  • 4陈兵.蛋白酶体抑制剂-硼替佐米在侵袭性恶性淋巴瘤治疗中的应用[J].药物与临床研究,2010,2:104-106.
  • 5Dolber PC, Jin H, Nassar R, et al. Thalidomide, lenalidomide andbortezomib in the management of newly diagnosed multiple myelo-ma [J].Expert Rev Hematol, 2011, 4(1): 51-60.
  • 6Greipp PR, Miguel JS, Dune BG, et al. International staging system-for multiple myeloma [J].J Clin Oncol, 2005, 23: 3412-3420.
  • 7Cancer Therapy Evaluation Program Common Terminology Criteriafor Adverse Events, Version3.0. DCID, NIC. DHHD [S/OL].[200303-03-31].http://ctep.cancer.gov/.
  • 8Mitsiades N,Mitsiades CS,Richardson PG, et al. The proteasomeinhibitor PS-341 potentiates sensitivity of multiple myeloma cellsto conventional chemotherapeutic agents: therapeutic application[J].Blood, 2003,101(6): 2377-2380.
  • 9Hideshima T, mitsiades C, Akiyam M, et al. Molecular mechanismsmediating antimyeloma activity of proteasome inhibitor PS-341 [J].Blood, 2003, 101: 1530-1534.
  • 10Raijumar SV, Richardson PG, Hideshima T, et al. Proteasome inhibi-tion as a novel therapeutic target in human cancer [J], Clin Oncol,2005, 23(3): 630-639.

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