摘要
支气管哮喘常表现为不同的炎症表型,特异性生物标志物是不同炎性致病机制下的特定产物,它可以反映当前哮喘炎症浸润程度。通过分析嗜酸性粒细胞型、中性粒细胞型、白三烯型跟其他类型炎症表型哮喘相关的特异性生物标志物的水平,可以鉴别不同的哮喘表型,有助于进一步了解哮喘患者炎性细胞浸润程度和特点,预测哮喘恶化,进一步指导哮喘治疗和管理。
Different inflammatory phenotypes are commonly manifested in asthma. Specific biomarkers are the products of diverse inflammatory pathogenic mechanism. Through the analysis of different specific biomarkers related to five major phenotypes such as eosinophilic phenotype, neutrophilic phenotype, leukotriene phenotype and mixed phenotype, it is available to discriminate diverse inflammatory phenotypes. Moreover, it renders it liable to obtain a better understanding of the extent of current inflammation and the possibility of exacerbation, thus contributing to a better therapy and management of asthma.
出处
《中华临床医师杂志(电子版)》
CAS
2014年第7期110-114,共5页
Chinese Journal of Clinicians(Electronic Edition)