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Early Goal Directed Sedation, a bridge to better clinical outcomes 被引量:16

Early Goal Directed Sedation, a bridge to better clinical outcomes
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摘要 Critical care has become a central part of modern medicine and an integral essential to improve the outcomes in acute care.The increasing complexity of surgical procedures,severity of co-morbid diseases,life expectancy and societal expectation is likely to escalate the burden and the global need for critical care resources.While millions of patients are ventilated worldwide every year,projections suggest that the number of ventilated patients is expected to rise by 31% over the following decade.1 Critical care has become a central part of modern medicine and an integral essential to improve the outcomes in acute care.The increasing complexity of surgical procedures,severity of co-morbid diseases,life expectancy and societal expectation is likely to escalate the burden and the global need for critical care resources.While millions of patients are ventilated worldwide every year,projections suggest that the number of ventilated patients is expected to rise by 31% over the following decade.1
作者 Yahya Shehabi
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2014年第10期1969-1972,共4页 中华医学杂志(英文版)
关键词 SEDATION early goal directed sedation ventilation critically ill DEXMEDETOMIDINE sedation early goal directed sedation ventilation critically ill dexmedetomidine
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  • 1Needham DM, Bronskill SE, Calinawan JR, Sibbald W J, Pronovost PJ, Laupacis A. Projected incidence of mechanical ventilation in Ontario to 2026: Preparing for the aging baby boomers. Crit Care Med 2005; 33: 574-579.
  • 2Wunsch H, Kahn JM, Kramer AA, Rubenfeld GD. Use of intravenous infusion sedation among mechanically ventilated patients in the United States. Crit Care Med 2009; 37: 3031- 3039.
  • 3Devlin JW, Mallow-Corbett S, Riker RR. Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit. Crit Care Med 2010; 38: S231.
  • 4Devlin JW. The pharmacology of oversedation in mechanically ventilated adults. Curr Opin Crit Care 2008; 14: 403-407.
  • 5Devlin JW, Roberts RJ. Pharmacology of commonly used analgesics and sedatives in the ICU: benzodiazepines, propofol, and opioids. Anesthesiology Clinics 2011; 29: 567-585.
  • 6Foster J. Complications of sedation and critical illness. Crit Care Nurs Clin North Am 2005; 17: 287-296.
  • 7Pandharipande P, Girard T, Jackson J, Morandi A, Thompson J, Pun B, et al. Long-term cognitive impairment after critical illness. New Engl J Med 2013; 369: 1306-1316.
  • 8Jackson JC, Pandharipande PP, Girard TD, Brummel NE, Thompson JL, Hughes CG, et al. Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study. Lancet Respir Med 2014, Epub ahead of print.
  • 9Barr J, Fraser GL, Puntillo K, Ely EW, G61inas C, Dasta JF, et al. Clinical Practice Guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41: 263-306.
  • 10Patel SB, Kress JR Sedation and analgesia in the mechanically ventilated patient. Am J Respir Crit Care Med 2012; 185: 486- 497.

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