青光眼睫状体炎综合征房水前列腺素E_2含量的变化

Changes of aqueous humor PGE_2 concentration in Posner-Shlossman syndrome

目的探讨青光眼睫状体炎综合征(青睫综合征)房水前列腺素E2(PGE2)含量的变化。方法青睫综合征患者21例(21只眼),分别在给予非甾体类消炎药治疗前后采用放射免疫法测量房水PGE2浓度,拟行超声乳化联合人工晶状体植入术的年龄相关性白内障患者21例(21只眼)设为对照。结果应用非甾体类消炎药治疗前试验组房水PGE2平均浓度为(45.39±5.82)ng/L,对照组房水中PGE2平均浓度为(12.46±2.87)ng/L,差异有显著性意义(P<0.05);试验组经非甾体类消炎药治疗后,房水PGE2浓度下降至(23.78±3.67)ng/L(P<0.05)。结论青睫综合征房水PGE2浓度升高。

Objective To investigate the changes of aqueous humor prostaglandin E 2 （ PGE2 ） concentration in pa-tients with Posner-Shlossman syndrome （ PSS） .Methods The aqueous humor concentration of PGE 2 was tested with radio-immunoassay in 21 cases （21 eyes） diagnosed with PSS before and after NSAID treatment .Twenty-one cases （21 eyes） with age-related cataract were also enrolled as the control .Results A significant difference was noted in aqueous humor concentration of PGE2 between two groups （45.39 ±5.82） ng/L vs.（12.46 ±2.87） ng/L;The aqueous humor concen-tration of PGE2 decreased significantly from （45.39 ±5.82） ng/L to （23.78 ±3.67） ng/L in the experimental group after NSAID treatment.Conclusions The aqueous humor concentration of PGE 2 increased in patients with PSS .