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TRAIL在保乳术后复发患者中的表达及意义 被引量:1

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摘要 乳腺癌是女性继肺癌之后发病率最高的恶性肿瘤,每年影响全球130万多名女性,在癌症相关性死亡中约占14%的。乳腺癌的发病率在过去的几十年中逐步增加,在未来几年预计将大幅上升。因此,乳腺癌仍将是一个巨大的健康负担。保乳手术在国内开展多年,复发率为28%~73%[1]。影响乳腺癌保乳术后复发转移的因素很多,包括患者年龄、肿瘤大小、腋窝淋巴结转移个数、肿瘤细胞分化程度、雌激素受体状态等[2,3]。
出处 《河北医药》 CAS 2014年第10期1529-1530,共2页 Hebei Medical Journal
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  • 2Voduc KD,Cheang MC, Tyldesley S,et al. Breast cancer subtypes and therisk of local and regional relapse. JCO ,2010,28 :1684-1691.
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  • 6Lannin DR, Haffty BG. End results of salvage therapy after failure ofbreast conservation therapy. Oncology, 2004,18 : 272-279.
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