Cu(acac)_2催化酰胺与卤代烃偶联反应研究

Cu(acac)_2 Catalyzed Amide Coupling Reactions with Halogenated Hydrocarbons

酰胺参与的C-N交叉偶联反应有着重要的应用价值。研究得乙酰丙酮铜盐催化,碳酸钾作为碱性试剂的酰胺芳基化反应很温和,且只使用10mol%的催化量催化剂就能达到很好的催化效果。

Amide cross - coupling reactions involving C - N have an important application value. The amide arylation reaction was achieved under a very mild condition with copper acetylacetonate as a catalyst and potassi- um carbonate as a base. Only 10 mol% of the catalyst can achieve a good catalytic effect.