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依托考昔超前镇痛用于皮肤扩张器植入术的疗效观察 被引量:1

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摘要 目的:观察依托考昔应用于皮肤扩张器植入术超前镇痛的临床效果。方法:选择ASAⅠ~Ⅱ级拟行皮肤扩张器植入术患者80例,随机分为依托考昔超前镇痛组(超前镇痛组)和对照组,每组40例。所有患者均采用手术常规使用1%盐酸利多卡因局部麻醉,均于1 h内完成。观察用药前后血压、心率、血氧饱和度的变化,术后1、2、4、8、16 h测定血浆皮质醇(Cor)、促肾上腺皮质激素(ATCH)、β-内啡肽(β-EP)水平,同时进行视觉模拟评分(VAS评分),记录不良反应发生情况。结果:用药前后血压、心率、血氧饱和度的变化比较两组无明显差异(P>0.05);超前镇痛组患者在术后4 h内各时间点Cor、ATCH、β-EP水平均显著低于对照组(P均〈0.05);超前镇痛组患者在术后1、2、4、8 h VAS评分均低于对照组(P〈0.05),术后1 h时的VAS评分两组比较差异有显著性(P〈0.05)。结论:依托考昔对皮肤扩张器植入术超前镇痛的疗效良好,且简单安全,不良反应少,患者满意度提高。
作者 张鑫 邱平阳
出处 《实用医学杂志》 CAS 北大核心 2014年第10期1638-1639,共2页 The Journal of Practical Medicine
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