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血红素氧化酶-1（HO-1）在前列腺癌的作用研究进展 被引量：1

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摘要 前列腺癌（prostate cancer,PCa）是男性泌尿系统常见的恶性肿瘤之一,早期诊断在临床防治中具有重要意义.目前在临床上诊断方面主要依赖的传统肛门指诊、B型超声、PSA等检测手段难以在前列腺癌早期将其检出;因此,有无其他前列腺癌早期（诊断）生物标志能够对早期前列腺癌做出诊断引起了广大学者的广泛关注和研究.血红素氧化酶-1（HO-1）作为一种血红素降解过程中的限速酶,和其分解产物在激素耐受性前列腺癌和激素非耐受性前列腺癌的新血管生成、增殖、转移、侵袭能力等方面发挥着重要作用.本文就近几年对HO-1在前列腺癌发生进展中的作用以及其在前列腺癌诊治中的潜在应用价值作一综述.
作者 戴谦 马建华 张向波 万江厚 白进良
机构地区 兰州大学第一附属医院泌尿外科
出处 《国际泌尿系统杂志》 2014年第3期384-388,共5页 International Journal of Urology and Nephrology
关键词 前列腺肿瘤 血红素氧化酶(脱环)
分类号 R737.25 [医药卫生—肿瘤]
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参考文献25

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二级参考文献12

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国际泌尿系统杂志
2014年 第3期

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