唐氏综合征筛查策略的经济学系统评价

Systematic review of economic evaluation of Down's syndrome screening strategy

目的:系统评价唐氏综合征产前筛查策略的经济性。方法:检索与唐氏综合征产前筛查经济学评价相关的文献,对纳入文章进行质量评价,运用描述性方法系统评价筛查策略的经济性。结果:根据纳入和排除的标准,共纳入15篇文献。纳入文献经质量评价、描述性分析对文献的基本信息、评价方法、评价结果进行系统总结。结论:从社会成本的角度,对孕妇进行DS筛查是具有成本效果的医疗保健措施,将年龄筛查、超声筛查和血清学筛查针对孕期综合筛查策略有较大的优势,其中对筛查的成本效果较好。

Objective： To systematically review the economy of prenatal screening strategy for Down＇s syndrome. Methods： The literatures about economic evaluation of prenatal screening of Down＇s syndrome were searched, the quality of the literatures was evaluated, descriptive analysis was used to systematically evaluate the economy of prenatal screening strategy for Down＇s syndrome. Results： A total of 15 literatures were included into the study according to the inclusion criteria and exclusion criteria. Quality of the studies included was evalu- ated, descriptive analysis was used to systematically summarize the basic information, evaluation methods and outcomes. Conclusion： From the perspective of social costs, Down＇s syndrome screening among pregnant women is cost - effective, the advantages of age screening, ultrasonic screening and serological screening are large for comprehensive screening strategy, and the cost effectiveness is good.