食物过敏与儿童腹痛

Food allergy and abdominal pain in children

腹痛是食物过敏引起的常见症状。可以是某些消化系统疾病的主要症状,如婴儿腹绞痛等;也可是某些疾病的伴随症状,如嗜酸细胞性胃肠炎等;或是全身性疾病的表现,如过敏症等。食物过敏引起腹痛等消化系统症状与口服免疫耐受建立的不完善,肠道菌群紊乱,肠道黏膜机械屏障的损伤,食物抗原的跨上皮运输,嗜酸细胞在肠道内的聚集以及食物抗原对胃肠道动力的影响有关。

Abdominal pain is a common symptom of food allergy. It may be the main symptom of some diseases of digestivesystem,such as infant colic. It may be accompany symptom ofsome diseases,such as eosinophilic gastroenteritis,or it is amanifestation of systemic disease,such as anaphylaxis. Oraltolerance development,bacterial intestinal microflora,intestinal barrier function,transepithelial transport of food antigens,eosinophil recruitment in the gastrointestinal tract,and effectof food allergens on gastrointestinal motility are the contribution to pathophysiology of gastrointestinal food allergy.