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安体舒通在慢性肾炎减少尿蛋白治疗中的研究 被引量:1

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摘要 目的探讨应用血管紧张素转化酶抑制剂(ACEI)和(或)血管紧张素受体拮抗剂(ARB)降低尿蛋白未达标慢性肾炎患者加用安体舒通,观察降低尿蛋白及肾脏保护作用。方法将24例长期应用ACEI和ARB尿蛋白未达标患者联合安体舒通20 mg/d。检测0、2、4、8、16周后24 h尿蛋白、血肌酐、血钾、估算肾小球滤过率(eGFR)。结果治疗后第8、16周时尿蛋白较治疗前明显下降;且eGFR、血肌酐、血钾无显著变化。结论在应用ACEI和ARB基础上联合安体舒通对降低慢性肾炎患者尿蛋白有显著作用。
作者 李东虎
出处 《中国实用医药》 2014年第10期173-174,共2页 China Practical Medicine
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