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ARTN蛋白在人类肿瘤发生发展中的作用研究进展 被引量：1

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摘要 ARTN蛋白是神经胶质细胞源性神经营养因子（GDNF）家族配体（GFL）的一个亚型，是GDNF 家族的第4个成员，亦属于转化生长因子β（ TGF-β）超家族［1］。近年来的研究表明， ARTN蛋白具有促进细胞趋化、黏附和迁移的作用，因此在介导肿瘤细胞侵袭、转移中具有重要的意义。现将ARTN蛋白在乳腺癌、胰腺癌、食管癌、胃肠道肿瘤、肺癌等肿瘤发生发展中的作用综述如下。
作者 郭敬 范开席
机构地区 山东省医学科学院附属医院 济南大学 山东省医学科学院医学与生命科学学院
出处 《山东医药》 CAS 2014年第14期96-98,共3页 Shandong Medical Journal
基金 山东省医药卫生科技发展计划项目(2013WS0371)
关键词 肿瘤 调控 生长 侵袭转移
分类号 R730.2 [医药卫生—肿瘤]
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参考文献20

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  • 4Banerjee A, Wu ZS, Qian PX, et al. ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A Signalling [ J]. PloS One, 2012,7 ( 11 ) : 50098.
  • 5Wu ZS, Pandey V, Wu WY, et al. Prognostic significance of the expression of GFRα1, GFRα3 and Syndecan-3, proteins binding ARTEMIN, in mammary caroinoma[ J]. BMC cancer, 2013,13 (1) :34.
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  • 7朱栋良,罗地来,罗刚,王博,高基民.Artemin、GFRα3在胰腺癌中的表达及其与胰腺癌神经浸润转移的相关性[J].南方医科大学学报,2009,29(3):428-431. 被引量：12
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二级参考文献62

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山东医药
2014年 第14期

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