期刊文献+

血清学标记物在炎症性肠病中的研究进展 被引量:5

Advances in Studies on Serological Markers in Inflammatory Bowel Disease
下载PDF
导出
摘要 炎症性肠病(IBD)作为一种病因尚未完全明确的慢性非特异性肠道炎性疾病,在我国的发病率呈明显上升趋势。目前IBD的诊断主要依靠内镜结合组织病理学检查,但检查为侵入性,操作复杂。寻找一种简单、准确的诊断方法成为目前亟待解决的问题。应用血清学标记物诊断IBD是近年来的研究热点。本文就血清学标记物在IBD中的研究进展作一综述。 Inflammatory bowel disease (IBD) is a chronic non-specific intestinal inflammatory disease and its etiology has not yet been clarified. The prevalence of IBD increases every year in our country. So far, the combination of endoscopy and histopathologieal examination is considered as the main method for the diagnosis of IBD, however, it' s an invasive method with a complex procedure. Searching for a simple and accurate diagnosis method has been an eager task. Recently, serological marker has become a hot spot of study in the diagnosis of IBD. This article reviwed the advances in studies on serological markers in IBD.
出处 《胃肠病学》 2014年第4期245-247,共3页 Chinese Journal of Gastroenterology
关键词 炎症性肠病 生物学标记 诊断 预后 Inflammatory Bowel Disease Biological Markers Diagnosis Prognosis
  • 相关文献

参考文献27

  • 1Wang YF,Ouyang Q,Hu RW.Progression of inflammatory bowel disease in China[J].J Dig Dis,2010,11 (2):76-82.
  • 2Prideaux L,De Cruz P,Ng SC,et al.Serological antibodies in inflammatory bowel disease:a systematic review[J].Inflamm Bowel Dis,2012,18 (7):1340-1355.
  • 3高翔,胡品津,何瑶,廖山婴,彭穗,陈旻湖.炎症性肠病患者血清中自身抗体检测的临床意义[J].中华内科杂志,2005,44(6):428-430. 被引量:39
  • 4Manolakis AC,Kapsoritakis AN,Georgoulias P,et al.Moderate performance of serum S100A12,in distinguishing inflammatory bowel disease from irritable bowel syndrome[J].BMC Gastroenterol,2010,10:118.
  • 5Kovacs M,Lakatos PL,Papp M,et al.Pancreatic autoantibodies and autoantibodies against goblet cells in pediatric patients with inflammatory bowel disease[J].J Pediatr Gastroenterol Nutr,2012,55 (4):429-435.
  • 6Kuna AT.Serological markers of inflammatory bowel disease[J].Biochem Med (Zagreb),2013,23 (1):28-42.
  • 7吴小平,莫雅娴.炎症性肠病非侵入性标志物研究进展[J].国际消化病杂志,2009,29(1):61-64. 被引量:12
  • 8Joossens S,Reinisch W,Vermeire S,et al.The value of serologic markers in indeterminate colitis:a prospective follow-up study[J].Gastroenterology,2002,122(5):1242-1247.
  • 9Charles N.Bernstein,Michael Fried,J.H.Krabshuis,Henry Cohen,R.Eliakim,Suleiman Fedail,Richard Gearry,K.L.Goh,Saheed Hamid,Aamir Ghafor Khan,A.W.LeMair,Malfertheiner,Qin Ouyang,J.F.Rey,Ajit Sood,Flavio Steinwurz,Ole O.Thomsen,Alan Thomson,Gillian Watermeyer,杨钊斌,杨川华,钱本余.2010年世界胃肠病学组织关于炎症性肠病诊断和治疗的实践指南[J].胃肠病学,2010,15(9):548-558. 被引量:102
  • 10Arias-Loste MT,Bonilla G,Moraleja I,et al.Presence of anti-proteinase 3 antineutrophil cytoplasmic antibodies (anti-PR3 ANCA) as serologic markers in inflammatory bowel disease[J].Clin Rev Allergy Immunol,2013,45(1):109-116.

二级参考文献64

  • 1戴军,刘文忠,赵永平,胡运彪,戈之铮.粪乳铁蛋白与炎症性肠病的相关性研究[J].中华消化杂志,2006,26(6):393-395. 被引量:8
  • 2何晓生,兰平.抗酿酒酵母抗体在克罗恩病的研究进展[J].中华实验外科杂志,2006,23(12):1585-1587. 被引量:2
  • 3Vergara T, Cofre P, Cifuentes S,et al. Presence of antineutrophil cytoplasmic antibodies (ANCA) and anti saccharomyces cerevisiae antibodies (ASCA) among patients with ulcerative colitis. Rev Med Chil, 2006,134 : 960-964.
  • 4Saxon A, Shanahan F, Landers C. A distinct subset of antineu trophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol,1990,86:202-210.
  • 5Roozendaal C, Kallenberg CG. Are anti-neutrophil cytoplasmic antibodies (ANCA) clinically useful in inflammatory bowel disease (IBD)? Clin Exp Immunol, 1999,116 : 206-213.
  • 6Anand V, Russell AS, Tsuyuki R, et al. Perinuclear antineutrophil cytoplasmic autoantibodies and anti saccharomyces cerevisiae antibodies as serological markers are not specific in the identification of Crohn's disease and ulcerative colitis. Can J Gas troenterol, 2008,22 : 6-33.
  • 7Brimnes J,Nielsen OH,Wiik A,et al. Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis. Dig Dis Sci,1999,44:415-423.
  • 8Lawrance IC, Murray K, Hall A, et al. A prospective comparative study of ASCA and pANCA in Chinese and Caucasian IBD patients. Am J Gastroenterol, 2004,99 : 2186-2194.
  • 9Basu D, Lopez I, Kulkarni A, et al. Impact of race and ethnicity on inflammatory bowel disease. Am J Gastroenterol,2005, 100: 2254-2261.
  • 10Ruemmele FM, Targan SR , Levy G, et al. Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease. Gastroenterology, 1998,115 : 822-829.

共引文献201

同被引文献45

引证文献5

二级引证文献37

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部