硅油基磁流体作为玻璃体腔填充物的力学特性

An experimental study of silicone-based magnetic fluid implanted into the vitreous cavity

目的 从力学的角度探讨新型的硅油基Fe3O4磁流体作为玻璃体填充物的可行性.方法 实验力学研究.首先将硅油基Fe3O4磁流体在猪眼玻璃体腔内作为填充物进行了实验,观察了硅油基Fe3O4磁流体在磁场作用下在玻璃体腔内表面的运动特性.其次将硅油基Fe3O4磁流体填充到模拟眼球内,并将模拟眼球悬挂在梯度磁场中,测出该液体的作用力.结果 硅油基Fe3O4磁流体在巩膜壁内可随磁力线方向移动并聚集.测得硅油基Fe3O4磁流体作用于模拟眼球内壁的压力为17 mmHg.结论 该硅油基Fe3O4磁流体基本上符合玻璃体填充物的要求,并具有独特的移动及定位优点.为磁性液体应用于视网膜修复提供了初步的研究及应用价值.

Objective This paper describes a new type of silicone-oil-based Fe3O4 magnetic liquid and discusses the feasibility of vitreous implants from the mechanics viewpoint.Methods This was an experimental study.The silicone-oil-based Fe3O4 magnetic liquid had been studied previously in the pig eye cavity.The experimental results demonstrated that the silicone-oil-based Fe3O4 magnetic liquid moves on the cavity surface and aggregates at some position under the action of the magnetic field force.The silicone-oil-based Fe3O4 magnetic liquid was filled into a simulated eyeball that was suspended in a gradient magnetic field.The force applied on the simulated eyeball was measured.Results The silicone-oil-based Fe3O4 magnetic liquid moved on the simulated eye cavity surface and aggregated along the magnetic field line with an applied pressure of about 17 mmHg.Conclusion The silicone-oil-based Fe3O4 magnetic liquid approximates the vitreous implant requirements,and has unique mobile and location advantages.This provides a preliminary study approach and an estimate of usefulness for magnetic liquid used in retinal repair.