摘要
Wnt信号通路是一条非常保守的信号转导途径,在许多生理过程中发挥了重要作用。Wnt信号通路与细胞的生长、分化、迁移及凋亡等诸多过程相关。由于该通路的异常活化与非小细胞肺癌(NSCLC)的发生、发展密切相关,因此揭示该通路的分子生物学机制与基因表达调节规律有重要意义。该文就Wnt信号通路与NSCLC研究近况予以综述。
Wnt signaling pathway is a highly conservative signal transduction pathway playing an impor-tant role in many physiological processes. Wnt signaling pathway are related with cell growth, differentiation,migration and apoptosis,and many other processes. Since the abnormal activation of this pathway is closelycorrelated with the occurrence and development of non-small cell lung cancer（NSCLC） ,revealing the molec-ular mechanisms and gent expression regulation of this pathway is important. Here is to make a review of therecent research of Wnt signaling pathway in NSCLC.
出处
《医学综述》
2014年第8期1386-1388,共3页
Medical Recapitulate
