摘要
急性淋巴细胞白血病(ALL)是一组异质性疾病,其治疗和预后具有很大的异质性。借鉴儿童ALL成功的治疗经验,成人ALL的治疗已有了很大改善。随着对ALL致病机制和各临床亚型生物学特征研究的不断深入、生物靶向治疗的研究进展、造血干细胞的发展及个体化治疗的应用,成人ALL的疗效必将进一步提高。该文总结成人急性淋巴细胞白血病的治疗方法,并对其预后因素进行分析。
Acute lymphocytic leukemia （ALL） is a heterogeneous group of diseases, the treatment and prognosis of which varies widely. Learning from the experience in the treatment of children ALL, the treatment of adult ALL improved markedly. With the deepening research of ALL pathogenic mechanisms and clinical subtypes biological characteristics, the research progress of biological targeted therapy, the advances of hematopoitic stem cell transplantation, and the application of individualized treatment, the efficacy of adult ALL is bound to further improve. Here is to make a review of the treatment methods of adult ALL, and analyzes its prognostic factors.
出处
《医学综述》
2014年第8期1445-1447,共3页
Medical Recapitulate
