不同年龄小儿化脓性扁桃体炎与肺炎支原体感染的关系分析

Analysis of the Relationship between Suppurative Tonsillitis and Mycoplasma Pneumoniae Infection in Children of Different Age Groups

目的探讨不同年龄小儿化脓性扁桃体炎与肺炎支原体（MP）感染的关系。方法将2007年8月至2012年8月房县人民医院收治的220例化脓性扁桃体炎患儿作为试验组，其中6个月至3岁者120例、4～13岁者100例；180例呼吸道感染患儿作为对照组，其中6个月至3岁者101例、4～13岁者79例，检测两组不同年龄患儿的MP-IgM与MP—IgE阳性率及白细胞介素13（IL-13）水平；采用红霉素半剂量[12mg／（kg·d）]联合罗红霉素半剂量[3．0mg／（kg·d）]进行治疗，对临床疗效进行分析。结果（D对照组与试验组6个月至3岁患儿MP-IsM、MP—IgE阳性检测率比较差异无统计学意义（P〉0．05），但两组IL-3水平差异有统计学意义（P〈0．05），4-13岁患儿上述各指标比较差异有统计学意义（P〈0．01）；②试验组6个月至3岁与4-13岁患儿的上述各指标差异有统计学意义（P〈0．01）；③经治疗本组220例化脓性扁桃体炎患儿l周内症状基本消失，部分患儿仍有刺激性咳嗽，经序贯治疗后消失。结论年龄为6个月至3岁患儿化脓性扁桃体炎-9MP感染无关，但4～13岁患儿化脓性扁桃体炎与MP感染存在较大的相关性。

Objective To investigate the relationship between suppurative tonsillitis and mycoplasma pneumoniae（MP） infection in children of different age groups. Methods A total of 220 cases （ including 120 cases aged 6 months to 3 years and 100 cases aged 4 years to 13 years） of suppurative tonsillitis（ trial group） and 180 cases（ including 101 cases aged 6 months to 3 years and 79 cases aged 4 years to 13 years） of children with respiratory tract infection（ control group） admitted to People＇s Hospital of Fangxian County in Hubei Province from Aug. 2007 to Aug. 2012 were included in the study, and the MP-IgM, MP-IgE and IL-13 of the two groups were detected. Semi-therapeutic dose[ 12 mg/（ kg· d）] of erythromycin joint with half therapeutic dose [ （3.0 rag,/ （kg · d） ] of roxithromycin were applied as treatment, and the clinical effect was analyzed. Results （1）There was no statistical difference of positive test rate of MP-IgM, MP-IgE in the 6 months to 3 years old subgroup between the control group and the trial group （ P 〉 O. 05 ）, but there were statistical differences of the level of IL-13 between the two groups （ P 〈 0.05 ）. there were statistically significant differences in the 4-13 years old subgroup of the above indexes between the two groups（ P 〈0.01 ） ; （2） There were statistically significant differences between the 6 months to 3 years old subgroup and 4 years to 13 years old subgroup in the above indexes in the trial group ;（3）after treatment, the symptoms of suppurative ton sillitis disappeared in one week in the trial group, some children still had irritating cough, which disappeared after sequential treatment. Conclusion There was no correlation between purulent tonsillitis and MP infection in 6 months to 3 years old children, but a considerable correlation between them exists in 4-13 years old children.