中西医结合治疗小儿过敏性紫癜的临床观察

Clinical Observation of Traditional Chinese Medicine and Western Medicine Integrated Treatment of Pediatric Allergic Purpura

目的探讨中西医结合治疗小儿过敏性紫癜的临床疗效。方法选取2010年1月至2012年8月唐山市丰南区医院收治的125例过敏性紫癜患儿为研究对象。将患儿按照随机数字表法分为两组,常规治疗组62例,采用常规治疗;联合治疗组63例,采用中西医结合治疗。比较两组患儿的临床疗效、住院时间以及复发率等。结果治疗后,联合治疗组的总体疗效显著高于常规治疗组(z=1.970,P<0.05),并且联合治疗组的外感风热型、血热妄行型、气虚不摄型、阴虚火旺型的显效率均高于常规治疗组患儿,但是组间差异无统计学意义(P>0.05)。联合治疗组患儿的住院时间及复发率均显著低于常规治疗组(P<0.05)。结论中西医结合方法治疗小儿过敏性紫癜的疗效显著,可明显改善患儿的临床症状,缩短患儿住院时间,降低复发率,值得临床广泛推广应用。

Objective To investigate the curative effect of TCM-WM integrated treatment of pediatric allergic purpura. Methods Total of 125 allergic purpura children in Fengnan District Hospital from Jan. 2010 to Aug. 2012 were included as research subjects,and were divided into conventional therapy group and combined therapy group according to the random number table method. Conventional therapy group（62 cases） was treated by conventional therapy and combined therapy group （63 cases） was treated by the combination therapy. The curative effect,length of stay, and recurrence rate of file two groups was compared. Results After treatment, the overall therapeutic effect of combined therapy group was significantly higher than conventional therapy group （z = 1. 970,P 〈 0.05 ）, the efficacy of the exogenous wind-heat type, hemopyretic bleeding type, deficient QI failing to control type, hyperactivity of fire caused by deficiency of YIN type were all higher than the convention-al therapy group, but the differences were not statistically significant （P 〉 0.05 ）. Hospitalization and relapse rate of combined therapy group were significantly lower than that of conventional therapy group（P 〈0.05 ）. Condusion The effect of integrated TCM-WM for treatment of pediatric allergic purpura is better which can significantly improve the clinical symptoms,lower the hospitalization and relapse rates,and it is worthy of wide application.