非那雄胺联合坦索罗辛治疗老年前列腺增生症(BPH)80例临床疗效观察

Clinical observation of effects of finasteride combined with tansuoluoxin in treatment of 80 cases with benign prostatic hyperplasia

目的:观察非那雄胺联合坦索罗辛治疗前列腺增生症的临床疗效。方法:将80例患者随机分成两组,治疗组患者采用非那雄胺联合坦索罗辛治疗,对照组患者单用非那雄胺治疗。两组患者均治疗1年,分别在3个月、6个月与1年,分别记录IPSS评分,MFR前列腺体积和残余尿量等指标,比较两组临床疗效。结果:治疗组治疗后IPSS评分明显下降,最大尿流率升高,残余尿量减少,前列腺体积减小,以上指标均明显优于对照组;治疗组总有效率92.5%,高于对照组的72.5%,两者比较有统计学意义(P<0.05)。结论:非那雄胺联合坦索罗辛治疗前列腺增生症(BPH),可减轻前列腺症状,改善最大尿流率,减少尿潴留及前列腺源性血尿及手术干预的发生率。

Objective：To observe clinical effects of finasteride combined with tansuoluoxin for benign prostatic hyperplasia（BPH）. Methods：80 patients were randomly divided into treatment group（treated with finasteride and tansuoluoxin） and control group（only treated with finasteride）. The two groups were treated for 1 year. The clinical efficacy was compared between the two groups 3 months,6 months,and 1 year after the treatment. Results： The total effective rate of treatment group was significantly higher than that of control group. Conclusions： Finasteride combined with tansuoluoxin for benign prostatic hyperplasia（BPH） can alleviate the clinical symptoms,improve the maximal urinary flow rate,and reduce the incidence of uroschesis and hematuria.