介入速尿肾动态显像在肾积水诊断及治疗中的临床应用价值

目的：探讨介入速尿的肾动态显像对先天性肾积水患者肾功能的评价及其在诊治方面的应用价值。方法选择门诊及住院经B超或其它检查诊断为肾积水患者63例，其中男46例，女17例；年龄11~61岁，平均年龄（35.37±24.26）岁。正常对照组患者71例，其中男52例，女19例；年龄29~58岁。平均年龄（40.14±18.13）岁。接受常规99mTc-DTPA肾动态显像，动态采集20min后静脉注射速尿并继续采集20min，计算肾小球滤过率（GFR）及半排时间（T1/2）。结果轻度肾积水18例，中度肾积水23例，重度肾积水22例，随着肾积水程度的加重，患肾的肾小球滤过功能受损程度加剧，半排时间延长，同时对利尿试验的反应明显减弱直至无反应。结论利尿肾动态显像对于肾积水治疗方案的选择和预后判断具有重要的临床指导意义。

Objective To evaluate the clinical value of diuretic renal dynamic imaging in patients with congenital hydronephrosis for the evaluation of renal function,diagnosis and curative effect. Methods 63 patients with congenital hydronephrosis who were either outpatient or in hospital were diagnosed by B ultrasonic or other examination. 46 patients were male,17 patients were female. about 11 to 61 years old,average 35.37±24.26）years old. Furosemide was injected 20 minutes after the injection of imaging agent 99mTc-DTPA. we calculated glomerulus filtration rate（GFR）and half washout time（T1/2）. Results Hydronephrosis were more aggravate,glomerular filtration function extent of damage was worse. Half washout time is delay.meanwhile,they reacted to Furosemid become weaken until no reaction. Conclusion Diuretic renal dynamic imaging may have great significance in selecting therapeutic method and prognosis of hydronephrosis.