期刊文献+

酵母编码区及非编码区的统计分析 被引量:3

Statistical Analysis of Coding Region and Non-coding Region of Yeast Genome
下载PDF
导出
摘要 以酵母全基因组中第一类的 2 50 5个编码序列和相对应的非编码序列为统计样本 ,给出了酵母编码起始区和编码终止区以及非编码区碱基的分布特征 .我们发现 ,真核生物的 Yeast和原核生物的 E.coli同样 ,四种碱基在编码区呈 3周期分布 ,非编码区没有 3周期特性 .在起始密码子前 -3位点上碱基 A、C、T明显偏置 ,与 Marilyn Kozak的结果相比较看出 ,这一位点与进化无关 .+4位点碱基 T、G的使用和脊椎生物不同 。 Based on the 2505 coding sequence and relative non coding sequence of the first category of yeast genes as statistical sample,the distribution of bases in the coding starting region, coding terminal region and non coding region of Yeast is given.We find that Yeast is familiar with E.coli. Four kinds of bases show 3 period distribution in coding region and not show it in non coding region. Base A、C、T are biased distinctly at the site -3. Compared with the results of Marilyn Kozak,the base distribution on this site is not correlate with evolution. The use of bases T、G at site +4 in yeast is different form slot in vertebrate and may be related with evolution.
出处 《内蒙古大学学报(自然科学版)》 CAS CSCD 北大核心 2001年第2期147-151,共5页 Journal of Inner Mongolia University:Natural Science Edition
基金 国家自然科学基金!( 39660 0 35)资助项目 内蒙古工业大学校青年基金资助课题
关键词 酵母全基因 编码起始区 编码终止区 3周期性 碱基 统计分析 酵母编码区 非编码区 Yeast genome coding starting region coding terminal region 3 period bias
  • 相关文献

参考文献8

二级参考文献16

  • 1于长春,程焉平,王庆华.蛋白质合成终止的研究进展[J].生命的化学,1996,16(4):27-29. 被引量:1
  • 2李宏,J Theor Biol,1996年,181卷,111页
  • 3罗辽复,内蒙古大学学报,1995年,26卷,690页
  • 4罗辽复,Bull Math Biol,1991年,53卷,345页
  • 5李宏,内蒙古大学学报,1998年,29卷,2期,172页
  • 6李宏,J Theor Biol,1996年,181卷,111页
  • 7李宏,内蒙古大学学报,1998年,29卷,6期,777页
  • 8Li Hong,J Theor Biol,1996年,181卷,111页
  • 9李宏,内蒙古大学学报,1999年,30卷,2期,177页
  • 10李宏,内蒙古大学学报,1998年,29卷,2期,172页

共引文献12

同被引文献34

  • 1[2]Duret L,Mouchiroud D.Expression pattern and,surprisingly,gene length shape codon usage in Caenorhabditis,Drosophila and Arabidopsis[J].Proc Natl Acad Sci USA,1999,96(8):4482-4487.
  • 2[3]Carlini D B,Chen Y,Stephan W.The relationship between third-codon position nucleotide content,codon bias,mRNA secondary structure and gene expression in the drosophild alcohol dehydrogenase genes Adh and Adhr[J].Genetics,2001,159(2):623-633.
  • 3[4]Sajau H,Washio T,Saito R,et al.Correlation between sequence conservation of the 5' untranslated region and codon usage bias in Mus musculus genes[J].Gene,2001,276(1-2):101-105.
  • 4[5]Stenstr(o)m C M,Jin H N,Major L L,et al.Codon bias at the 3'-side of the initiation codon is correlated with translation initiation efficiency in Escherichia coli[J].Gene,2001,263(1-2):273-284.
  • 5[6]Fedorov A,Saxonov S,Gilbert W.Regularities of context-dependent codon bias in eukaryotic genes[J].Nucleic Acids Res,2002,30(5):1192-1197.
  • 6[7]Ohno S.Universal rule for coding sequence construction:TA/GC deficiency-TG/CT excess[J].Proc Natl Acad Sci USA,1988,85(24):9630-9634.
  • 7[8]Karlin S,Campbell A M,Mrazek J.Comparative DNA analysis across diverse genomes[J].Annu Rev Genetics,1998,32:185-225.
  • 8[10]Rodriguez-Trelles F,Tarrio R,Ayala F J.Switch in codon bias and increased rates of Amino Acid substitution in the Drosophila saltans species group[J].Genetics,1999,153(1):339-350.
  • 9[11]Moriyama E N,Powell J R.Gene length and codon usage bias in Drosophila melanogaster,Saccharomyces cerevisiae and Escherichia coli[J].Nucleic Acids Res,1998,26(13):3188-3193.
  • 10[12]Moriyama E N,Powell J R.Codon usage bias and tRNA abundance in Drosophila[J].J Mol Evol,1997,45(5):514-523.

引证文献3

二级引证文献72

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部