降钙素配合低频脉冲电磁场治疗骨质疏松症的临床研究

The clinical research on the treatment of osteoporosis with calcitonin and low frequency pulse electromagnetic field

目的:探讨降钙素配合低频脉冲电磁场治疗骨质疏松症的临床疗效。方法:选取84例原发性骨质疏松患者,随机分为对照组和治疗组,每组42例。两组均给予碳酸钙、维生素D等常规药物治疗。在此基础上对照组肌内注射鲑鱼降钙素,治疗组肌内注射鲑鱼降钙素并配合低频脉冲电磁场治疗。并分别评估治疗前及治疗后3个月、6个月患者的疼痛疗效及检测骨密度。结果:两组患者治疗后疼痛较治疗前均明显减轻,治疗时间越长,疼痛减轻越明显;治疗3个月、6个月后,治疗组骨密度较对照组均有显著提高,其差异有统计学意义(t=3.129,t=6.457;P<0.05);两组均未发生严重的不良反应。结论:骨质疏松症患者在常规治疗的基础上肌内注射鲑鱼降钙素并配合低频脉冲电磁场进行治疗,可明显减轻患者的疼痛,并增加骨密度。经统计学分析,该治疗方法疗效确切,不良反应少,具有一定的临床借鉴意义。

Objective： To explore the clinical research on the treatment of osteoporosis with calcitonin and Low frequency pulse electromagnetic field. Methods： Selected 84 cases of primary osteoporosis were randomly divided into control group and treatment group, 42 cases in each group, two groups were given calcium, vitamin D and other drugs conventional treatment, on the basis of the control group, intramuscular injections salmon calcitonin in the treatment group andResults： Two groups of patients after treatment, the pain was significantly reduced compared with before treatment,the longer the treatment, the more obvious decline; Treatment of three months, six months later, the treatment group compared with the control group bone mineral density were significant differences（t=3.129, t=6.457; P〈0.05）; The two groups no serious adverse reactions. Conclusion： Osteoporosis patients in the conventional therapy treatment based on intramuscular injection of salmon calcitonin and with PEMF treatment can significantly reduce the patient＇s pain, increase bone density, efficacy, adverse reactions, with some clinical reference significance.