湖北某地区农村人群2型糖尿病及糖尿病前期横断面调查

Preliminary Cross-sectional Survey of Type 2 Diabetes Mellitus and Prediabetes in a Rural Population in Some Area of Hubei Province

目的了解湖北省农村人群2型糖尿病（T2DM）和糖尿病（DM）前期患病率及其高危因素。方法采用随机抽样方法,选取湖北省10 800名40岁以上乡镇居民（天门市）进行横断面调查。对所有研究对象行问卷调查和常规体格检查,采用OGTT诊断T2DM,留取空腹和餐后2h静脉血进行相关生化检查。结果①湖北省乡镇居民（天门市）T2DM总患病率为9.99%,男性为10.09%,女性为9.93%。DM前期患病率为18.4%,男性18.8%,女性18.1%。②男性和女性T2DM的患病率均随着年龄的增长而增加,70岁以上人群患病率达到最高。③男性的DM前期患病率在50～59岁之间最高,女性在70岁以上最高。④多元Logistic回归分析显示年龄、血压、脉搏、腰围身高比（WHTR）、腰臀比（WHR）、体重身高指数（BMI）、饮酒史、甘油三酯（TG）、总胆固醇（TC）均为T2DM和DM前期的高危因素,其中脉搏增快显著增加T2DM和DM前期患病风险（分别为OR=1.34,95%CI 1.25～1.44;OR=1.30,95%CI 1.23～1.37）。结论湖北省农村人群（天门市）T2DM及DM前期的患病率较高,均高于全国DM患病率普查水平,应采取措施进一步加强对农村人群DM的防治和宣教。

Objective To examine the prevalence and risk factors of type 2diabetes mellitus（T2DM）and prediabetes in a rural population in Hubei province.Methods Random sampling method was used to recruit 10 800rural residents aged over 40 years for this cross-sectional study.All subjects completed the questionnaire and underwent the physical examination.Fasting and postprandial 2hblood samples were obtained for the biochemical tests.An oral glucose-tolerance test（75g OGTT）was used to diagnose T2DM.Results ①The prevalence of T2DM was 9.99%in the cohort of rural population,10.09%in males and 9.93%in females.The prevalence of prediabetes was 18.4%in this population,18.8%in males and 18.1%in females,respectively.②The prevalence of T2DM increased with age in both genders.The prevalence of T2DM was highest in over 70 years group.③The prevalence of prediabetes was highest in 50-59years group in males,and over 70years group in females.④ Multivariate analysis showed that age,hypertension,pulse,waist height ratio（WHTR）,waist hip ratio（WHR）,body mass index（BMI）,drinking habit,triglyceride（TG）,total cholesterol（TC）were the risk factors of T2DM and prediabetes.Among these risk factors,the increased pulse was positively correlated with T2DM and prediabetes（OR=1.34,95%CI：1.25-1.44; OR=1.30,95%CI：1.23-1.37）.Conclusion The prevalence of T2DM and prediabetes in rural populations in Hubei province is higher than the national level.Measures should be taken to strengthen the prevention,treatment and education of T2DM and prediabetes in rural populations.