Haff病误诊三例报告并文献复习

Three Misdiagnosed Patients with Haff Disease: A Report and Literature Review

目的探讨Haff病临床特点,分析其误诊原因并提出防范措施。方法回顾分析我院近期收治误诊的Haff病3例的临床资料,并复习相关文献。结果本文2例以乏力就诊,1例以腹痛、恶心及呕吐就诊,就诊初期3例分别误诊为上呼吸道感染、胃肠炎及心肌炎,后经追问病史并结合临床表现及实验室检查结果确诊为Haff病,予补液、利尿及碱化尿液治疗均痊愈。结论对其认识不足、忽视病史询问及未行相关实验室检查是导致Haff病误诊的主要原因。

Objective To explore the clinical features of Haff disease and to analyze the misdiagnosis causes in order to provide the preventive measures. Methods Clinical data of 3 patients with Haff disease was retrospectively analyzed,and related literature was also reviewed. Results Two patients visited doctors for fatigue and another patient for abdominal pain, nausea and vomiting. The three patients were misdiagnosed as having upper respiratory tract infection,gastroenteritis and myo-carditis respectively in initial period,and Haff disease was confirmed after enquiring related history combined with results of clinical manifestations and laboratory examination. All the patients were cured after treatments of fluid replacement,dieresis and urine alkalization. Conclusion The main misdiagnosis causes of the Haff disease are lack of knowledge and negligence of history enquiry without related laboratory examinations.