准分子激光原位角膜磨镶术前近视患者干眼发病及相关因素调查

SURVEY OF DRY EYE DISEASE AND ITS RELATIVE FACTORS IN MYOPIA PATIENTS BEFORE LASIK SURGERY

目的调查准分子激光原位角膜磨镶术(LASIK)术前近视患者干眼发病情况及相关因素。方法对拟行LASIK手术的近视患者100例术前记录其性别、年龄、屈光不正状态,包括:屈光度(等效球镜)、视力矫正方式(框架镜/隐形眼镜)、视力矫正效果(正矫/欠矫)。对这些患者分别进行OSDI问卷调查、角膜荧光素染色、泪液分泌功能检测和泪膜稳定性检测,随后依据特定的诊断标准进行干眼诊断并对确诊患者干眼程度进行分级。结果 LASIK术前近视患者中诊断为干眼的患者比例为50%。干眼是否发病与患者性别和年龄无关,与屈光度相关,其中轻度和中度近视患者之间干眼发病率无明显差异,高度近视患者干眼发病率则明显升高,但干眼程度不随屈光度的升高而加重。佩戴隐形眼镜者的干眼发病率高于佩戴框架镜者。视力欠矫者干眼发病率高于正矫者。结论 LASIK术前屈光不正患者中干眼的发病率较高,特别是高度近视、佩戴隐形眼镜及视力欠矫患者,因此术前非常有必要进行干眼筛查并及时给予相应治疗和心理辅导以获得良好的治疗效果和手术满意度。

ObjectiveTo investigate the incidence and relative factors of dry disease in myopia patients before LASIK surgery.Methods The data of 100 patients＇ gender,age,diopter,mode of refractive correction（spectacle/contact lens）,effects of vision correction（corrected/not corrected）were recorded before LASIK surgery.All patients underwent an OSDI interviewer-study,tear breakup time, schirmer testing with anesthetic,fluorescent staining.Dry eye disease was diagnosed and graded depend on the results.Results The overall prevalence of dry eye was 50%.Gender and age had no relationship with dry eye other than diopter.There was no significantly difference between mild and moderate myopia.The prevalence of dry eye in high myopia patients was higher,but the degree of dry eye did not rise along with the rise of diopter.Contact lens wears were higher than spectacle wears.Vision correction patients were higher than vision not corrected patients.Conclusions The incidence of dry eye of refractive error patients is higher,especially in those patients who are high myopia and wore contact lens and vision not corrected.Full-scale dye eye checks and corresponding treatments should be taken when necessary.