恩度联合经肝动脉化疗栓塞术治疗中晚期肝癌的疗效观察

Clinical efficacy of endostar combined with hepatic artery chemoembolization in the treatment of advanced liver cancer

目的探讨恩度联合经肝动脉化疗栓塞术治疗中晚期肝癌的临床效果。方法回顾性分析2011年10月至2013年4月间收治的50例中晚期肝癌患者的临床资料。其中,观察组25例,采用恩度联合经肝动脉化疗栓塞术治疗;对照组25例,采用单纯肝动脉化疗栓塞术治疗。结果观察组患者总有效率、1年生存率均明显高于对照组,术后1个月和6个月的肿瘤转移率明显低于对照组,差异有统计学意义(P<0.05);两组患者治疗后甲胎蛋白水平均明显低于治疗前,治疗前后差异有统计学意义(P<0.05)。结论恩度联合经肝动脉化疗栓塞术治疗中晚期肝癌的临床效果良好,值得推广。

Objective To observe the clinical effect of endostar combined with hepatic artery che- moembolization in the treatment of advanced liver cancer. Methods The clinical data of 50 cases of patients with advanced liver cancer who had been treated in our hospital from October 2011 to April 2013 were retro- spectively analyzed. Results The total efficiency, one-year survival of patients in the observation group were significantly higher and the tumor metastasis after a month and a half year was significantly higher than those of the control group, the differences were statistically significant （P 〈 0. 05 ） ; A fetoprotein levels of two groups of patients after treatment were significantly lower than that of before treatment, the difference was statistically significant （P 〈 0. 05）. Conclusion The clinical effect of endostar combined with hepatic artery chemoembolization in the treatment of advanced liver cancer was good, so is worthy of promotion.