Zero-P椎间融合术与椎间植骨融合术在颈椎间盘病变中的应用

Application of Zero-P intervertebral fusion and intervertebral bone graft fusion to treatment of cervical intervertebral disc lesions

目的比较颈椎Zero-P椎间融合术与椎间植骨钛板内固定术在单节段颈椎间盘病变中的治疗效果。方法选择我院收治的单节段颈椎间盘突出症患者50例,随机分为Zero-P椎间融合术的观察组或椎间植骨钛板内固定术的对照组,每组25例,对比两组术中情况、手术前后JOA评分、椎体融合率、术后症状缓解率及并发症发生率。结果观察组手术时间、术中出血及取髂骨时间均显著低于对照组(P<0.05);两组术后3和12个月的JOA评分均显著优于术前(P<0.05);两组椎体融合率无显著差异(P>0.05);观察组症状缓解率显著优于对照组(P<0.05)。结论 Zero-P椎间融合术手术时间短、术中出血少、症状缓解率高,且术后并发症少,值得临床推广。

Objective To compare the clinical effects of Zero-P intervertebral fusion versus intervertebral bone graft combined with titanium plate fixation to the treatment of single-level cervical intervertebral disc lesions. Methods Fifty patients with single-level cervical disc herniation admitted to our hospital were randomly and equally divided into observation group（ treated by Zero-P intervertebral fusion） and control group（ treated by intervertebral bone graft combined with titanium plate fixation）. The two groups were compared in terms of intraoperative conditions,preoperative and postoperative JOA scores,vertebral fusion rate,symptom remission rate,and complication rate. Results The observation group had a significantly shorter operation time,significantly less intraoperative blood loss,and a significantly shorter duration of iliac bone harvesting,as compared with the control group（ P〈0. 05）. Both groups showed significant increases in JOA scores at 3 and 12 months after operation（ P〈0. 05）. There was no significant difference in intervertebral fusion rate between the two groups（ P〉0. 05）. The observation group had a significantly higher symptom remission rate than the control group（ P〈0. 05）. The control group had a significantly higher complication rate than the observation group（ P〈0. 05）. Conclusions Zero-P intervertebral fusion has the advantages of short operation time,little intraoperative blood loss,high symptom remission rate,and few postoperative complications and holds promise for clinical application.