普米克令舒联合博利康尼治疗小儿毛细支气管炎的临床研究

Clinical Research of Pulmicort and Bricanyl in the Treatment of Children with Bronchiolitis

目的:探讨普米克令舒与博利康尼联合治疗小儿毛细支气管炎的临床效果。方法:选择2011年5月-2013年5月笔者所在医院收治的毛细支气管炎患儿154例,采用随机数字表法分为联合组与对照组,各77例。两组均给予常规治疗,联合组在常规治疗的基础上给予普米克令舒与博利康尼联合雾化吸入治疗;对照组患儿采用地塞米松治疗。结果:联合组住院时间及各临床症状消失时间均优于对照组(P<0.05)。联合组治疗的总有效率为97.40%,明显高于对照组的79.22%,两组比较差异有统计学意义(P<0.05)。结论:在常规治疗基础上,普米克令舒与博利康尼联合雾化吸入治疗小儿毛细支气管炎,可以有效改善患儿呼吸情况,扩张支气管平滑肌,且具有激素抗炎优势,疗效显著,适于临床推广。

Objective：To investigate the clinical effect of Pulmicort and Bricanyl combined in the treatment of children with bronchiolitis.Method：154 cases of children in our hospital from May 2011 to May 2013 with bronchiolitis were selected,which were randomly divided into combine treatment group and control group,each of 77 cases,two groups were given conventional treatment,combine treatment group received Pulmicort and Bricanyl combined inhalation therapy on the basis of conventional treatment;control group were treated with dexamethasone on the basis of conventional treatment.Result：The hospitalization time and the clinical symptoms disappeared time in the combine treatment group were better than that in the control group（P〈0.05）.The total effectiveness of combine treatment group was 97.40%,significantly higher than 79.22%in control group,there was statistical difference（P〈0.05）.Conclusion：Pulmicort and Bricanyl combined atomization inhalation in the treatment of bronchiolitis can effectively improve respiratory conditions,expansion of bronchial smooth muscle,and hormone anti-inflammatory advantage on the basis of conventional treatment,with a significant effect,it is suitable for clinical application.