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玻璃体视网膜交界面超微结构及其年龄相关性改变 被引量：6

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摘要 玻璃体视网膜交界面由玻璃体基底部、玻璃体后皮质与视网膜内界膜构成.玻璃体基底部借Ⅱ型胶原垂直插入内界膜形成紧密连接,玻璃体后皮质区则经“分子胶”模型、新糖蛋白模型及核纤层蛋白细胞模型形成相对松散的连接.随着年龄增长,玻璃体基底部后缘会逐渐向后延伸形成新的紧密连接,而玻璃体后皮质区则会由于内界膜增厚、基质降解酶浓度升高、自由基累积等致使玻璃体视网膜交界面粘连作用减弱,甚至形成玻璃体后脱离.玻璃体黄斑牵拉综合征、黄斑裂孔、孔源性视网膜脱离等玻璃体视网膜交界面疾病均被证实与玻璃体视网膜交界面状态密切相关.正确认识玻璃体视网膜交界面超微结构及年龄相关性改变是了解玻璃体视网膜交界面疾病的基础.
作者 张辰茜 陈有信
机构地区 中国医学科学院北京协和医学院北京协和医院眼科
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2014年第3期328-331,共4页 Chinese Journal of Ocular Fundus Diseases
关键词 玻璃体 超微结构 视网膜 超微结构 年龄因素 综述
分类号 R774.1 [医药卫生—眼科]
  • 相关文献

参考文献47

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二级参考文献69

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共引文献4

同被引文献39

  • 1马昱,姜燕荣,殷春悦,黎晓新.玻璃体黄斑牵引综合征的临床及光相干断层扫描图像特征[J].中华眼底病杂志,2005,21(2):86-89. 被引量：12
  • 2高付林,张卯年,王炜,杨炳建.高度近视后巩膜葡萄肿黄斑劈裂光学相干扫描图像特征[J].中国实用眼科杂志,2005,23(5):547-550. 被引量：17
  • 3Ponsioen TL, Hooymans JM ,Los LI. Remodelling of the human vitreous and vitreoretinal interface - - a dynamic process. Prog Retin Eye Res 2010 ;29 :580-595.
  • 4Ponsioen TL, van der Worp RJ, van Luyn MJ, et al. Packages of vitreous collagen (type II) in the human retina: an indication of postnatal collagen Turnover? Exp Eye Res 2005 ; 80 : 643 -650.
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  • 10Hayreh SS, Jonas JB. Posterior vitreous detachment: clinical correlations. Ophthalmologica 2004 ;218 :333-343.

引证文献6

二级引证文献24

中华眼底病杂志
2014年 第3期

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