药物流产后出血患者宫腔残留组织结果分析

Ultrasound and Pathological Analysis of Intrauterine Residual Tissue in Patients with Vaginal Bleeding after Drug Abortion

目的通过B型超声及清宫送病理两种不同方法检测药物流产后阴道出血时间延长患者宫腔内残留组织,探讨米非司酮药物流产后阴道出血时间延长与残留组织(蜕膜/绒毛)的关系。方法对2011年6月-12月144例药物流产后出血患者根据出血时间是否延长(>15 d),从B型超声情况及清宫病理情况分别研究。结果 B型超声提示:出血时间≤15 d的96例患者中20例有宫腔残留物,出血时间>15 d的48例患者中20例有宫腔残留物,两组比较,差异有统计学意义(P<0.05)。清宫病理提示:出血≤15 d与出血>15 d宫腔残留组织病理构成比较差异无统计学意义(P>0.05)。结论药物流产后阴道出血时间延长与宫腔残留有关,与残留组织是否为绒毛或蜕膜无关。

Objective To examine the intrauterine residual tissue in patients with prolonged vaginal bleeding after drug abortion by both B-ultrasound and pathology through cleaning the remnant of uterine, in order to investigate the relationship between prolonged vaginal bleeding after medical abortion with mifepristone and the residual tissues （decidua/viUi）. Methods Between June and December 2011, 144 patients with vaginal bleeding after medical abortion were involved in the study. B-ultrasound and pathology through cleaning the remnant of uterine were adopted to study the residual tissue respectively. Results Based on the ultrasound results, the difference in residual tissues was statistically significant between patients with bleeding for 15 days or shorter and patients with bleeding for more than 15 days （P 〈 0.05）. The pathological results showed that the difference in decidua and villi on the residual tissues was not statistically significant between patients with bleeding for 15 days or shorter and patients with bleeding for more than 15 days （P 〉 0.05）. Conclusion After drug abortion, the prolonged vaginal bleeding was correlated with intrauterine residual tissues, and was not correlated with whether the residual tissue was villi or decidua.