声门旁副神经节瘤1例并文献复习

Paraglottic space primary paraganglioma:a case report and review

目的:探讨声门旁副神经节瘤的临床特征、诊断及治疗方法。方法:报告1例声门旁副神经节瘤,并复习相关的国内外文献。结果:患者表现为声音嘶哑,给予气管切开及颈侧切开术后治愈。术后免疫组织化学分析神经元特异性烯醇化酶(NSE)、嗜铬蛋白A(CgA)均为阳性表达。结论:声门旁副神经节瘤非常罕见,诊断主要依靠病理及免疫组织化学检测。综合分析其临床病理特征,提高诊断的准确性,有效避免误诊。

Objective：To investigate the clinical feature, diagnose and therapeutic methods of paraglottic space primary paraganglioma. Method：One case of paraglottic space primary paraganglioma was reported and the relevant literatures were reviewed. Result：One case showed a hoarse voice, who was cured after the surgery of neck incision. NSE and CgA were positively expressed. Conclusion： Paraganglioma of the paraglottic space is very rare. The diagnosis of paraglottic space primary paraganglioma bases on histopathology and immunohistochemistry. The immunohistochemistry and clinical character must be comprehensively analyzed to increase the diagnosis accuracy.