期刊文献+

人乳头瘤病毒定性检测与液基薄层细胞学检查在绝经后宫颈癌前病变中的诊断价值分析 被引量:11

原文传递
导出
摘要 目的:探讨人乳头瘤病毒(HPV)定性检测与液基薄层细胞学检查(TCT)在绝经后宫颈癌前病变中的诊断价值。方法:对2012年1-6月在三亚市妇幼保健院门诊部就诊的350例绝经后患者行宫颈TCT及HPV检测,同时对其行阴道镜检查,并对可疑病变进行活检。结果:350例患者中,HPV感染率为26.57%(93/350),HPV检测诊断的敏感性为73.00%(73/100),特异性为86.80%(217/250),假阳性率为9.43%(33/350),假阴性率为7.71%(27/350);TCT检测诊断的敏感性为85.15%(86/101),特异性为97.19%(242/249),假阳性率为2.0%(7/350),假阴性率为4.29%(15/350)。结论:对于绝经后宫颈癌患者,联合应用HPV与TCT两种检测技术可以提高检出率。
出处 《中国妇幼保健》 CAS 北大核心 2014年第16期2586-2588,共3页 Maternal and Child Health Care of China
  • 相关文献

参考文献11

二级参考文献66

共引文献88

同被引文献80

  • 1刘春燕,卞美璐,耿力,赵方辉,章文华,陈汶,陈凤,马莉,胡尚英,王少明,许丽娜,乔友林.高危型人乳头状瘤病毒第二代杂交捕获试验筛查宫颈癌及其癌前病变的验证研究[J].中国肿瘤,2009,18(12):1008-1011. 被引量:5
  • 2徐华林,卢莺燕,林红梅,陶萍萍.不同人乳头状瘤病毒检测方法对宫颈高度病变的诊断价值[J].中华临床感染病杂志,2011,4(2). 被引量:3
  • 3M. GRAFLUND,B. SORBE,S. SIGURDARDóTTIR,M. KARLSSON.HPV-DNA, vascular space invasion, and their impact on the clinical outcome in early-stage cervical carcinomas[J]. International Journal of Gynecological Cancer . 2004 (5)
  • 4Vecchione A,Zanesi N,Trombetta G,et al.Cervical dysplasia, ploidy, and human papillomavirus status correlate with loss of Fhit expression. Clinical Cancer Research . 2001
  • 5Koopman L A,Corver W E,van der Slik A R,Giphart M J,Fleuren G J.Multiple genetic alterations cause frequent and heterogeneous human histocompatibility leukocyte antigen class I loss in cervical cancer. The Journal of experimental medicine . 2000
  • 6Bagarazzi ML, Yan J, Morrow MP, et al. Immunotherapy against HPV 16/18 gener- ates potent TH 1 and cytotoxic cellular im- mune responses[J]. Sci Transl Med, 2012, 4(155): 155.
  • 7Allia E, Ronco G, Coccia A, et al. Inter- pretation ofpl 6(INK4a)/Ki-67 dual im- munostaining for the triage of human pap- illomavirus-positive women by experts and nonexperts in cervical cytology[J]. Cancer Cytopathol, 2015, 123(4):212-218.
  • 8Peghini BC, Abdalla DR, Barcelos AC, et al. Local cytokine profiles of patients with eervieal intraepithelial and invasive neo- plasia[J]. Htan Inmltaol, 2012, 73(9).920-926.
  • 9JEMAL A, BRAY F, CENTER M M, et al. Global cancer statistics[J]. CA Cancer J Clin,2011,61 (2) :69-90.
  • 10BOSCH F X, LORINCZ A, MUNOZ N, et al. The causal relation between human papillomavirus and cervical cancer [ J ]. J Clin Patho1,2002 ,55 (4) :244-265.

引证文献11

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部