摘要
目的观察NT-proBNP对基层不稳定型心绞痛(UA)患者危险分层的价值。方法选择60例UA患者,检测血浆NT-proBNP与cTnI浓度,同时观察心电图ST段压低数值,并根据Gensini法进行冠状动脉病变积分计算。结果 60例患者中低危患者40例,高危患者20例。低危与高危患者血浆NT-proBNP浓度、ST段压低程度、cTnI浓度以及Gensini积分差异均有显著性(P<0.05)。将患者分为NT-proBNP>1 219 pg/mL组与≤1 219 pg/mL组,两组患者cTnI浓度、ST段压低程度与Gensini积分差异均有显著性(P<0.05)。此外,NT-proBNP与ST段压低程度、cTnI浓度与Gensini积分存在明显正相关(P<0.05)。结论 NT-proBNP能够作为UA患者早期危险分层的重要指标,对临床治疗有指导意义。
Objective To observe the value of NT-proBNP in risk stratification for unstable angina（UA） of grassroots patients.Methods 60 UA patients were chosen. Their plasma NT-proBNP and cTnI concentrations were detected, and ST segment depression values were observed. Gensini method was adopted to compute integrals of coronary disease. Results Among 60 patients, there were 40 low-risk patients and 20 high-risk patients. There were significant differences between low-risk patients and high-risk patients on plasma NT-proBNP and cTnI concentrations, ST segment depression levels and Gensini scores（P 0.05）. There were significant differences between NT-proBNP 1 219 pg/mL group and NT-proBNP≤1 219 pg/mL group on cTnI concentrations, ST segment depression levels and Gensini scores（P 0.05）.NT-proBNP was positively related to cTnI concentration, ST segment depression level and Gensini score（P 0.05）. Conclusions NT-proBNP can be taken as an important indicator of early risk stratification of UA patients, and it has guiding significance for clinical treatment.
出处
《临床医学工程》
2014年第5期569-570,共2页
Clinical Medicine & Engineering
基金
梅州市医学科技计划项目(项目编号:2013B154)
