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脑梗死合并2型糖尿病与血清高迁移率族蛋白B1关系的研究 被引量:4

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摘要 血清高迁移率族蛋白B1(HMGB1)是细胞炎性因子,可以促进胰岛素抵抗、糖耐量受损、糖尿病的发生和发展。同样,HMGB1与急性脑梗死亦息息相关,在急性脑梗死中HMGB1可过度表达,参与炎症反应、血脑屏障通透性调节、神经元凋亡等病理生理学过程,加重了脑梗死疾病的病情。因此作为炎性因子,HMGB1与脑梗死合并2型糖尿病疾病有很大关系。
机构地区 徐州医学院
出处 《实用医技杂志》 2014年第5期550-551,共2页 Journal of Practical Medical Techniques
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