吸烟与打鼾及阻塞性睡眠呼吸暂停低通气综合征关系的调查研究

Research on the Relationship between Smoking and Snoring and Obstructive Sleep Apnea Hypopnea Syndrome

目的调查吸烟与打鼾及阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的关系。方法于2010年3—5月采用多阶段随机整群抽样方法选择我市10个社区25岁以上常住居民进行入户调查,共调查3 624名,打鼾者1469名,从基线人群中随机选取打鼾>2级且经多导睡眠图检查确诊为OSAHS的患者100例,根据其是否吸烟分为吸烟组(56例)和不吸烟组(44例)。采用问卷调查,内容包括人口学信息、吸烟行为、打鼾分级等。OSAHS患者采用美国ALICE3型多导睡眠仪进行整夜睡眠呼吸监测,记录两组患者呼吸暂停低通气指数(AHI)和SaO2。结果打鼾人群吸烟率为40.64%(597/1 406),高于非打鼾人群的33.17%(715/2 155)(P<0.05);打鼾随着吸烟量的增加打鼾程度加重,组间比较差异有统计学意义(P<0.05);OSAHS患者吸烟组AHI高于不吸烟组,平均SaO2低于不吸烟组(P<0.05)。结论吸烟与打鼾及OSAHS的关系密切,吸烟量越大打鼾程度越严重。

Objective To survey the relationship between smoking and snoring and obstructive sleep apnea hypopnea syndrome（ OSAHS）. Methods 3 624 permanent people ≥25 years from March to May in 2010 in Anyang were selected by multi stage randomized cluster sampling method,the survey involved demographic information,smoking behavior,snoring classification. 1 469 people were snoring. 100 patients with OSAHS were divided into smoking group（ 56 cases） and non- smoking group（ 44 cases）. Both group were detected AHI and SaO 2. Results The smoking rate of snoring people was 40. 64%（ 597 / 1 406）,was higher than that of non- smoking people of 33. 17%（ 715 /2 155）（ P〈0. 05）. With the increase of amount of smoking,the degree of snoring increased（ P〈0. 05）; the AHI in smoking group was higher than that of non- smoking group, SaO 2 was lower（ P〈0. 05）. Conclusion The relationship between smoking and snoring and OSAHS is close,the larger amount of smoking,the more serious degree of snoring.