炔雌醇环丙孕酮治疗少数民族人群青春期功能失调性子宫出血的疗效观察

Observation on ethinylestradiol and cyproterone acetate′s therapeutic effect on treating puberty dysfunctional uterine bleeding in ethnic minority

目的探讨使用炔雌醇环丙孕酮(达英-35)治疗少数民族人群青春期功能失调性子宫出血(功血)的效果。方法对2011年5月至2013年5月于本院诊断为青春期功血的32例患者,予炔雌醇环丙孕酮治疗后观察月经周期、月经天数、血红蛋白和子宫内膜的厚度。结果经炔雌醇环丙孕酮治疗后,从第1次服用到出血量明显减少的时间为(19±6)h,完全止血时间为(32±7)h;患者月经周期规律,月经量减少,经期相对缩短(P<0.05),血红蛋白上升(P<0.05),子宫内膜变薄(P<0.05)。结论炔雌醇环丙孕酮治疗少数民族人群青春期功血取得较好的疗效,不良反应少、方便简单,值得在基层医院推广。

Objective Ethinylestradiol and cyproterone acetate （Diane-35）＇s therapeutic effect in treating puberty dysfunctional uterine bleeding in ethnic minority has been discussed. Methods Menstrual cycle, number of days, hemoglobin and endometrial thickness of 32 patients whose hospital diagnosis is puberty dysfunctional uterine bleeding from May 2011 to May 2013 have been observed after ethinylestradiol and cyproterone acetate treatment. Results After ethinylestradiol and cyproterone acetate treatment, the time, at which the bleeding significantly reduces, is （19 ± 6）h from the first time to taking medication. The time, at which the bleeding completely stops, is （32±7）h; the patients menstrual cycle became regular, the amount of menstrual was reduced, menstruation was relatively shortened（P〈0.05）, haemoglobin rose（P〈0.05） and endometrial became thin（P〈 0.05）. Conclusion Ethinylestradiol and cyproterone acetate has good therapeutic effect in treating puberty dysfunctional uterine bleeding in ethnic minority and it has less adverse reaction. It is simple and convenient, worthy of promotion in the primary hospital.