“荣脉散”对前部缺血性视神经病变PRVEP的影响观察

Observed the Effect of “Rong Mai San” on Anteriorischemicoptico-neuropaty Eye PRVEP

目的观察中药"荣脉散"对前部缺血性视神经病变棋盘格模式反转视觉诱发电位(PRVEP)的影响。方法收集2010年5月—2013年10月住院治疗的前部缺血性视神病变共58例,随机数字表法分为常规治疗组(对照组)30例,中药"荣脉散"干预组(治疗组)28例,对治疗组28例病例在进行常规治疗的基础上加服中药"荣脉散",观察PRVEP的变化,对2组治疗效果进行分析比较。结果治疗前对照组及治疗组的P100潜伏期及P100波幅值经统计学处理差异无统计学意义;治疗后对照组平均值:P100潜伏期为(107.40±1.45)ms,P100波幅为(3.34±0.11)μV,治疗组平均值:P100潜伏期为(92.60±1.97)ms,P100波幅为(3.74±0.18)μV,2组数据差异有统计学意义(P<0.05);对照组治疗前后的差值:P100潜伏期为(8.39±0.89)ms,P100波幅为(0.22±0.02)μV,治疗组治疗前后的差值:P100潜伏期为(21.95±1.30)ms,P100波幅为(0.58±0.03)μV,2组数据比较差异有统计学意义(P<0.05)。结论中药"荣脉散"治疗对前部缺血性视神病变的PRVEP值有明显的改善作用。

OBJECTIVE To observe the effect of “Rong Mai San” on the anteriorischemicoptico-neuropaty of the eye PRVEP. METHODS All of 58 anteriorischemicoptico-neuropaty inpatients were collected which from May 2010 to Oct 2013. Random distrubuted into two groups, including control group 30 and treatment group 28. Treatment group was administrated conventional therapy and oral “Rong Mai San”, and observed the change of PRVEP. Analysis and comparison effect of treatment in two groups. RESULTS Incubation period and amplitude of P100 no significant changes between two groups before treatment. After treatment, in control group, P 100 Incubation period average, （107.40±1.45）ms, P100 Amplitude （3.34±0.11）μV; in treatment group, P 100 Incubation period average （92.60±1.97）ms, P 100 Amplitude （3.74±0.18）μV. Compared with two groups, the difference was statistically significant（P〈0.05）. Difference between the control group before and after treatment： P100 Incubation period （8.39±0.89）ms, P100 amplitude （0.22±0.02）μV, the difference before and after the treatment group： P100 Incubation period （21.95±1.30）ms, P100 amplitude （0.58±0.03）μV. Compared with two groups, the difference was statistically significant （P〈0.05）. CONCLUSION The eye PRVEP ofanteriorischemicoptico-neuropaty is significantly improved by “RongMai San” treatment.