灵杆菌素、惠尔血治疗化疗病人白细胞下降的成本-效果分析

A Comprison of Cost-effectiveness Between GM-CSF and G-CSF in Treating Leucopenia in Chemotherapy of Cancer

目的 :观察灵杆菌素、惠尔血治疗化疗病人白细胞下降的疗效、不良反应及成本 -效果对比。方法 :运用药物经济学成本 -效果分析方法 ,对灵杆菌素和惠尔血治疗化疗病人白细胞下降的疗效及成本进行评价。结果 :灵杆菌素治疗化疗病人白细胞下降的有效率为80 % ,每周期人均费用为1008元 ,成本 -效果比为12 6 ;惠尔血的有效率为85 7 % ,每周期人均费用为2304元 ,成本 -效果比为26 88。结论 :灵杆菌素能有效地治疗化疗病人白细胞下降 ,成本

AIM:To compare the therapeutic effect,adverse reactions and the costs between GM-CSF and G-CSF in treating leucopenia in chemotherapy of cancer.METHODS:Using pharmacoeconomic cost-effectiveness analysis,GM-CSF was compared with G-CSF in treatment of leucopenia in chemotherapy of cancer.RESULTS:The effective rate of GM-CSF was 80% with an average cost of 1 008 yuan in a therapeutic course,the cost-effective ratio being12.6,and that of G-CSF was 85.7% with an average cost of 2 304 yuan,the cost-effective ratio being 26.88.CONCLUSION:GM-CSF can effectively treat leucopenia in chemotherapy of cancer,and its cost-effective ratio ia superior to that of G-CSF.GM-CSF is worthy to be used clinically.