3种治疗下呼吸道感染方案的成本-效果分析

The Cost-effectiveness Analysis of Three Therapeutic Schemes for Lower Respiratory Tract Infections

目的 :评价下呼吸道感染的3种治疗方案所产生的药物经济学效果。方法 :运用成本 -效果分析法对3种治疗方案进行分析。结果 :从有效率来看 ,青霉素 -哌拉西林组 (L1 组 )的成本 -效果比最小 ;从治愈率来看 ,头孢噻肟钠组 (L3)与L1 组的成本 -效果比无显著性差异 (P>0 05) ,而环丙沙星 -克林霉素组 (L2)的成本 -效果比明显高于L1 组和L3 组 (P<0.05)。结论 :L1 组为最佳治疗方案 ,L3 组虽然成本高 ,但治愈率也高 ,不良反应少 。

OBJECTIVE:To evaluate the pharmacoeconomic effectiveness of three therapeutic schemes for lower respiratory tract infections.METHODS:The cost-effectiveness analysis of three therapeutic schemes for lower respiratory tract infections was carried out.RESULTS:The cost-effectiveness ratio of penicillin-piperacillin schemes(L1)was minimum in respect to the effective rate.However,the cost-effectiveness ratios had no significant difference between cefotaxime scheme(L3)and L1 sche_me in regard to cure rate(P>0.05),the cost-effectiveness ratio of ciprofloxacin-clinadmacin scheme(L2) was higher significantly than those of L1 and L3 schemes(P<0.05,both schemes).CONCLUSION:L1 is the best therapeutic scheme.Although L3 scheme had higher cost,it had higher cure rate and lower ADRs occurrence.L3 scheme is benefitial to improvement of patient's life quality.