脾胺肽口服冻干粉治疗小儿厌食疗效观察

The Effect Observation of Spleen Amino Peptide Oral Lyophilized Powder in the Treatment of Infantile Anorexia

目的探讨脾胺肽口服冻干粉治疗小儿厌食症的疗效。方法随机选择我院2011年6月至2013年6月85例非器质性小儿厌食症患儿,随机分两组,观察组45例给予脾胺肽口服冻干粉治疗,对照组40例给予常规治疗,比较两组患儿临床疗效和治疗前、后血微量元素的变化。结果观察组临床治疗总有效率95.56%,显著高于对照组(72.5%),差异有统计学意义(P<0.05);两组患儿免疫球蛋白指标(IgA、IgM、IgG)比较差异显著(P<0.05),但两组血清铁、铜、镁、锌含量比较差异无统计学意义(P>0.05)。结论脾胺肽口服冻干粉治疗非器质性小儿厌食症的疗效显著,患者症状和微量元素水平明显改善,值得临床推广使用。

Objective To investigate the effect of Spleen Aminopeptide Oral Lyophilized Powder in the treatment of infantile ano-rexia. Methods 85 cases with infantile anorexia were randomly selected from June 2011 to June 2013 and were divided into two groups. The observation group （45 cases） was treated with Spleen Aminopeptide Oral Lyophilized Powder, while the control group （40 cases） was given regular treatment. Clinical curative effect and the change of blood trace elements before and after treatment were com-pared between the two groups. Results The total clinical effectiveness was 95.56% in the observation group, significantly higher than that of the control group （72.5%）, and there was statistical significance （P〈0.05）. Immunoglobulin indexes （IgA, IgM and IgG） of two groups were significantly different, and the observation group was significantly higher than that of control group （P〈0.05）, but the levels of serum iron, copper, magnesium, zinc content was not statistically different in two groups （P〉0.05）. Conclusion Spleen Aminopeptide Oral Lyophilized Powder has good effect in the treatment of infantile anorexia, and the patients＆#39; symptoms and trace ele-ments level have improved obviously. It is worthwhile to be widely applied clinically.