雾化吸入布地奈德联合支气管扩张剂治疗毛细支气管炎的疗效观察

Curative effect observation on atomization inhalation budesonide combined with bronchodilator therapy in the treatment of capillary bronchitis

目的探讨雾化吸入布地奈德联合支气管扩张剂治疗毛细支气管炎的安全性及有效性。方法将110例毛细支气管炎患儿随机分为观察组和对照组,每组55例,对照组患儿采用沙丁胺醇进行治疗,对观察组患儿采用沙丁胺醇联合布地奈德联合雾化吸入治疗,观察并比较两组患儿的临床疗效、临床症状、体征改善情况及药物不良反应。结果观察组的总有效率(90.9%)显著高于对照组(72.7%),观察组患儿喘憋、气促、咳嗽及肺部啰音消失时间均明显短于对照组(P<0.05);对照组有2例患儿心率加速,两组患儿均未发生严重不良反应。结论雾化吸入布地奈德联合支气管扩张剂治疗毛细支气管炎安全有效,可促进患儿恢复。

Objective To investigate safety and efficacy of atomization inhalation budesonide combined with bronchodilator in the treatment of capillary bronchitis. Methods From Apirl 2012 to June 2013, 110 cases of capillary bronchitis patients were randomly divided into observation group and control group, each group of 55 cases, control group were treated with salbutamol, observation group were treated with salbutamol and budesonide atomization inhalation therapy to observe and compare the clinical efficacy to improve clinical symptoms and signs and adverse drug reactions of two groups of children. Results The observation group total effective rate were（90.9%） significantly higher than the control group（72.7%）, observation group recovery time of suppress, shortness of breath, cough and lung＇s significantly shorter than the control group, the differences were statistically significant（P〈0.05）, two groups of children were not happened serious adverse reaction. Conclusion Atomization inhalation budesonide combined with capillary in the treatment of capillary bronchitis is safe and effective, so it can promote children recovery.