下呼吸道疾病的药物利用研究

Study on the Drug Utilization for Lower Respiratory Tract Diseases

目的 :观察下呼吸道疾病的药物利用状况和特点。方法 :应用急性生理及慢性健康评分法 (A PACHE)和限定日剂量 (DDD)数指标 ,分析上海市某医院 1993～ 1997年 2 90例下呼吸道疾病患者的用药状况 ,并研究APACHE与DDD数之间的相关性。结果 :在下呼吸道疾病的用药中 ,抗感染药和祛痰药占有很大比重 ,分别为 3 9.0 6%和 3 8.3 8%。研究未发现药品消耗量与疾病严重度之间预期的定量关系。结论 :用DDD数分析用药频度 。

To study the status and patterns of the drug utilization in the diseases of lower respiratory tract, the drug utilization for 290 inpatients with respiratory tract diseases in a Shanghai hospital druing 1993 1997 was analyzed by using Acute Physiology, Age, Chronic Health Evaluation(APACHE) and index of defined daily dose numbers(DDDs). The relativity between APACHE and DDDs was studied. It was found that most common drugs was anti infection agents and expectorants, accounting for 39.06?% and 38.38?%, respectively. The quantitative relationship between drug consumption and disease severity was not observed. It is concluded that the status of the drug utilization can't be demonstrated by analyzing the frequency of drug use by using DDDs.