大动脉粥样硬化性脑梗死患者复发的影响因素分析

Influencing factors of recurrent ischemic stroke in patients with large artery atherosclerosis

目的探讨大动脉粥样硬化性脑梗死患者复发的影响因素。方法选择首次发病的大动脉粥样硬化脑梗死患者200例为研究对象,分为复发组和非复发组。对患者临床资料进行分析,分析影响脑梗死复发的相关因素。结果多因素分析结果显示,年龄、LDL-C升高、糖尿病、阿司匹林抵抗和抗血小板药物依从性差是影响大动脉粥样硬化性脑梗死复发的独立危险因素(P<0.05或<0.01)。结论影响大动脉粥样硬化性脑梗死患者复发的因素主要有年龄大、合并糖尿病、LDL-C升高、阿司匹林抵抗以及抗血小板药物依从性差。

Objective To discuss influencing factors of recurrent ischemic stroke in patients with large artery atherosclerosis. Methods A total of 200 cases with cerebral infarction were divided into recurrent group and non-re-current group. Influencing factors of recurrent ischemic stroke in patients with large artery atherosclerosis were ana-lyzed by analyzing clinical data. Results Multiple-factor analysis showed that age, high level of LDL-C, diabetes mel-litus, aspirin resistance and poor compliance to antiplatelet drug were risk factors of recurrent ischemic stroke in pa-tients with large artery atherosclerosis （P〈0.05 or P〈0.01）. Conclusion Age, high level of LDL-C, diabetes mellitus, as-pirin resistance and poor compliance to antiplatelet drug are risk factors of recurrent ischemic stroke in patients with large artery atherosclerosis.