利拉鲁肽配合健康教育治疗初诊肥胖2型糖尿病的临床观察

Clinical observation of liraglutide with health education in treatment of fornewly diagnosed overweight patients with type 2 diabetes

目的观察利拉鲁肽配合健康教育治疗初诊肥胖2型糖尿病的疗效。方法对12例初诊肥胖2型糖尿病患者通过全面评估,根据评估结果对入选患者进行糖尿病相关健康教育,同时应用利拉鲁肽进行治疗12周,期间记录FBG、2hPG、HbA1c、BMI治疗前后的变化及低血糖等不良事件发生情况。结果 2例出现胃肠道反应,所有患者体重指数、空腹血糖、餐后血糖、血压、血脂、HbAlc均有改善,病人均无低血糖事件发生。结论应用利拉鲁肽配合健康教育治疗初诊肥胖2型糖尿病安全性高,疗效显著,是值得推荐的一种治疗选择。

Objective To observe the clinical effect of liraglutide with health education fornewly diagnosed overweight patients with type 2 diabetes. Methods Twelve cases of newly obese patients with type 2 diabetes were comprehensive evaluated, and thendiabetes related health education were implementedaccording to the evaluation results.at the same time, the patients were treated for 12 weeks with liraglutide. FBG, 2hPG, HbA1c BMI and the change of hypoglycemia and other adverse events were recorded during before and after treatment. Results The 2 cases of gastrointestinal reac-tion, the bodyweights, fasting blood glucoses,postprandial blood glucoses,HbA1c of all the patients decrease signifi-cantly, and BMI decreased more obviously, no hypoglycemic was observed. Conclusion The liraglutide treatmentwith health educationis ideal optionfor newlydiagnosed overweight patients with type 2 diabetes mellitus. It is a therapeutic optionrecommended.