新生儿巨细胞病毒感染临床分析及干预对策

Clinical analysis and intervention measures of neonates with cytomegalovirus infection

目的分析新生儿巨细胞病毒感染的危险因素、干预对策与护理。方法选择来我院就诊的巨细胞病毒感染患儿及健康新生儿,采用PCR、ELISA分别检测标本的CMV-DNA、CMV-IgG、CMV-IgM的水平。结果 95例新生儿尿液中50例CMV-DNA为阳性(52.63%),且其母亲乳汁CMV-DNA大多为阳性(90.00%);随着产妇年龄的增加,产妇CMV-IgM、CMV-IgG的阳性率均逐渐增加,其中产妇CMV-IgM差异有统计学意义,新生儿CMV-IgG均低于产妇CMV-IgG。结论加强对孕妇产前的产检是预防新生儿CMV感染的重要措施。

Objective To analyze the risk factors of neonatal cytomegalovirus infection and its intervention and nursing Methods The children with cytomegalovirns infection treated in our hospital and healthy newborns were selected. And PCR and ELISA were used to examine the level of CMV-DNA, CMV-IgG and CMV-IgM of sam- ples. Results For 95 examined urine, CMV-DNA of 50 cases were positive（52.63%）, and CMV-DNA of most mother＇s milk for 50 cases were positive （90.00%）. With the increase of the age of pregnant woman, the positive rate of CMV- IgM and CMV-IgG of CMV-IgG increased. And CMV-IgM of pregnant woman had evident difference, and CMV-IgG of newborns were lower than that of pregnant woman. Conclusion Enhancing prenatal examination is an important measure preventing neonatal cytomegalovirus infection.