急性脑梗死患者血浆NPY水平变化

Changes of Plasma NPY Levels in Patients With Acute Cerebral Infarction

目的 :观察脑梗死 (ACI)急性期血浆神经肽Y(NPY)的变化及临床意义。方法 :采用放射免疫分析法检测 5 0例急性脑梗死 (CI)患者血浆神经肽Y(NPY)浓度 ,并以 30例健康人作为对照。结果 :ACI患者血浆中NPY含量为 431.0 3± 142 .0ng/L显著高于正常对照组 145 .1± 44 .1ng/L(P <0 .0 0 1)。结论 :检测结果表明 。

Objective To investigate the changes of plasma NPY levels in patients with acute cerebral infarction and its clinical significance. Methods Plasma NPY levels were determined in 50 patients with acute ceretral infarction and 30 controls by RIA. Results Placma NPY contents in ACI patients (431.03±142.0ng/L) were significantly higher than those in the controls (1451.1±44.1ng/L; P<0.001). Conclusion NPY as a strong vasoconstrictive neuro peptide could be closely relcted to the mechanism of diseace in ACI.