贞芪扶正颗粒对肺肾阴虚型慢阻肺稳定期患者运动耐量及生活质量的影响

Clinical effects of Zhenqi Fuzheng granule on sports tolerance and life quality in COPD patients

目的:临床观察贞芪扶正颗粒能否改善肺肾阴虚型慢性阻塞性肺疾病稳定期患者运动耐量及生活质量。方法:将肺肾阴虚型慢阻肺稳定期患者65例,随机分为治疗组34例,对照组31例。两组患者均给予化痰、解痉、平喘治疗,治疗组加用贞芪扶正颗粒口服,疗程3个月。观察治疗前后两组患者肺功能,6MWT及CAT评分变化。结果:治疗后,治疗组FEV1、FEV1%较对照组及治疗前有显著提高(P<0.05)。治疗后,两组患者6MWT均较治疗前有明显增加(P<0.05或P<0.01),治疗组比对照组增加更加明显(P<0.05)。治疗后,两组患者CAT评分均较治疗前有明显下降(P<0.05或P<0.01),治疗组比对照组下降更加明显(P<0.05)。结论:贞芪扶正颗粒可以改善肺肾阴虚型慢性阻塞性肺疾病稳定期患者运动耐量及生活质量。

Objective：To observe clinical effects of Zhenqi Fuzheng granule on sports tolerance and life quality in COPD patients. Methods：65 patients were randomly divided into two groups. Both groups were given expectorant, antispasmodic, asthma, the treatment group was given Zhenqi Fuzheng granule more for 3 courses. Results：After treatment, FEV1,FEV1%in treatment group were obviously higher （P〈0.05）. 6MWT in two groups were enhanced （P〈0.05 or P〈0.01）, especially in the treatment （P〈0.05）. CAT scores in two groups were in contrary （P〈0.05 or P〈0.01）, especially in the treatment （P〈0.05）. Conclusion： Zhenqi Fuzheng granule can improve exercise tolerance and life quality in COPD patients.