脑宁康颗粒治疗急性缺血性脑卒中的临床疗效研究

Clinical Research of Naoningkang Granule on Acute Ischemic Stroke

目的观察脑宁康颗粒对急性缺血性脑卒中临床疗效。方法 183例急性缺血性脑卒中患者随机分为对照组和治疗组,对照组予基础治疗;治疗组予基础治疗+脑宁康颗粒。疗程:脑宁康颗粒治疗14 d,两组标准化基础治疗90 d。服药期间停服其他清热解毒、活血化瘀中药。结果两组神经功能缺损程度,Barthel指数,Rankin评分治疗前后比较提示治疗组疗效优于对照组(P<0.05)。经治疗14 d后,两组风火上扰证患者证候积分差异有统计学意义(P<0.05)。结论脑宁康颗粒能很好的改善神经症状,对缺血性脑卒中的治疗及功能恢复有确切的疗效。对风火上扰证患者有更好的治疗效果,另外对合并冠心病和高血压的患者疗效显著。

Objective： To observe the clinical efficacy of Naoningkang Granule on acute ischemic stroke. Methods： 183 patients with acute ischemic stroke were randomly divided into control group and treatment group. The control group was given standard therapy while treatment group was given standard therapy plus Naoningkang Granule. Naoningkang granule treatment： Naoningkang Granule therapy lasted 14 days while standard therapy lasted 90 days for both groups. Other herbs of heat-clearing and toxin-detoxicating,promoting blood circulation and removing blood stasis were stopped to use. Results： Nerve function defect degrce,Barthel index,Rankin scores before and after treatment of the two groups suggested the curative effect of treatment group was superior to that of control group. After 14 days of treatment,syndrome integral of patients with Fengreshangrao syndromes of the two groups has remarkable difference（P〈0.05）. Conclusion： Naoningkang Granule can improve neurological symptom and contribute to functional recovery of acute ischemic stroke. It has obviously therapeutic effect on patients with Fenghuoshangrao syndrome, especially for those with coronary heart disease and hypertension.