两种方法治疗颅内夹层动脉瘤临床对照研究

CONTROLLED CLINICAL STUDY ON TREATING INTRACRANIAL DISSECTING ANEURYSM WITH 2 METHODS

目的:比较血管内治疗与脑血管搭桥治疗颅内夹层动脉瘤的临床疗效。方法:回顾性分析河北省人民医院和协作医院2008年12月至2012年10月收治的24例颅内夹层动脉瘤患者的临床资料,其中血管内治疗组12例,脑血管搭桥治疗组12例,比较两组患者术前等待时间、并发症发生率及术后GOS预后评分。结果:血管内治疗组术前等待时间明显短于脑血管搭桥组、并发症发生率明显低于脑血管搭桥组,组间比较差异具有统计学意义(P<0.01,P<0.05);两组患者预后良好率比较差异无统计学意义(P>0.05)。结论:血管内治疗和脑血管搭桥都是临床治疗颅内动脉夹层动脉瘤的方法,从并发症发生率和术前等待时间看血管内治疗优于脑血管搭桥治疗。

Objective：To compare the curative effects on treating intracranial dissecting aneurysm with endovascular treatment and cerebral vascular bypass treatment.Methods：The clinical data of 24 cases intracranial dissecting aneurysm were retrospectively analyzed from 2008.12 to 2012.10 in Hebei People’s Hospital and cooperative hospitals. Among 24 patients, 12 patients received endovascular treatment, the other 12 patients received cerebral vascular bypass treatment. The preoperative waiting time, incidence of complications and postoperative GOS prognostic score of 2 groups were compared. Results： The preoperative waiting time of patients in endovascular treatment group was obviously shorter, incidence of complications were obviously lower than that of patients in cerebral vascular bypass treatment group （P〈0.01,P〈0.05）. There had no statistical difference about better prognosis rate between these 2 groups （P〉0.05）.Conclusions：Endovascular treatment and cerebral vascular bypass treatment are methods for treating intracranial dissecting aneurysm in clinic. But endovascular treatment is superior to cerebral vascular bypass treatment according to preoperative waitting time and incidence of complications.