42例晚期新生儿肺炎喉部病原菌分布分析

ANALYSIS OF PATHOGENIC BACTERIA DISTRIBUTION IN LARYNX OF 42 CASES LATE NEONATAL PNEUMONIA

目的:探讨郴州市桂阳县晚期新生儿肺炎喉部病原菌的分布特点及对抗生素的敏感性。方法:2011.7-2012.6我院收治的晚期新生儿感染性肺炎患儿,喉部分泌物培养阳性42例,分析病原菌的分布和药敏实验结果。结果:42例喉部分泌物培养阳性的患儿,革兰阳性菌主要为金黄色葡萄球菌、表皮葡萄球菌和溶血性葡萄球菌,革兰阴性菌主要为肺炎克雷伯菌和大肠埃希菌。本地区病原菌除对青霉素的敏感率较低外,革兰阳性菌对苯唑西林、哌拉西林、红霉素敏感率较高,革兰阴性菌对头孢曲松、头孢哌酮舒巴坦和氨曲南敏感率较高。结论:本地区病原菌对抗生素的敏感率虽然较高,但建议没有明确细菌感染及支原体感染证据者,尽量少用抗生素,以免影响常用药物的敏感率。

Objective： To investigate the distribution and sensitivity to antibiotics of pathogenic bacteria in larynx of late neonatal pneumonia in Guiyang County of Chenzhou.Methods： 42 cases late neonatal pneumonia that the throat secretion culture was positive were selected in our hospital from 2011.7 to 2012.6, and analyzed distribution of pathogenic 〈br〉 bacteria and results of drug sensitivity test.Results： In 42 cases, gram positive bacteria were staphylococcus aureus, staphylococcus epidermidis and staphylococcus haemolyticus; 2 main gram-negative bacteria were klebsiella pneumoniae and escherichia coli. In our region, only the sensitive rate of pathogenic bacteria to penicillin was low. The sensitive rate of gram positive bacteria to oxacillin, piperacillin and erythromycin was fairly higher; gram-negative bacteria were sensitive to ceftriaxone, cefoperazone sulbactam and aztreonam.Conclusions：Although the sensitive rate of pathogenic bacteria to antibiotics is fairly higher in this region, but also suggests sparing use of antibiotics if no clear bacteria or mycoplasma infection, so as not to affect the susceptibility of commonly used drugs.